I used a 280ai in elk and whitetail. No shots taken inside 300 yards non past 475 yards. It worked as good as any other standard action caliber. I personally don't care for it but it's a fine cartridge and does it's job just fine without burning powder by the ton!Never had one, what are the pro's & con's of the 280 AI vs 28 Nosler ? Don't want or need any input about other calibers. Preferably from folks who have worked with the calibers, not the I know a guy who knows a guy's brother who knows a guy ! Thanks in advance