One of my last posts was asking info for a varmint rifle. I was debating between the 204. Ruger and the 22-250 Remington. I am really interested in the 204. Ruger but i don think it is the caliber for me. I was talking to my hunting buddy's brother and he use to shoot a 243. win Parker Hale topped with a 6-24x scope which he used on ground hogs and coyotes. He was capable of reaching ranges past his 22-250 due to better resistance against wind, and had hard down range power and was just as flat if not flatter. he strongly suggest it. I am now in debate between the 243. win and the 22-250. win. It would be used on mainly coyotes, varmints, pests, and long range plinking. if i got the 243. win i would use it on whitetail or pronghorn as well. I currently own a 7mm rem mag and a 300. wsm and i dont know if i need a 243. win or just stick with the 22-250. I reload so im not worried about pricing. If i were to get the 22-250 it would probably be a Remington model 700 VS SF II and then i was looking at the Tikka T3 Laminated Stainless 243. win.