243 with good bullets does a great job on whitetail here, 95 or heavier seems to be the ticket. No complaints at all. I would consider it the perfect cartridge for anyone recoil sensitive who wants to take a few deer. The flat trajectory is great too! I have personally seen at least a dozen deer taken with my buddie's 243 with 95g bullets. Distances were 50 to 300 yards. Good terminal performance and seemed to consistently put them down fast with heart/lung shots.