Without a doubt, hunting big game with the Sierra MK bullet has been the most pondered, discussed, digested, regergitated and debated topic on this board. It barely takes the mention of the SMK to get someone all heated up.
YES, I was kidding.
As for my personal experience with the SMK on big game. I shot one large PA whitetail with a SMK bullet from my Weathery 7mm mag rifle. Although I did not perform an autopsy, the deer had a sizable hole blasted out the far side of its chest and expired quickly. I considered that shot to be in the X ring.