I shot a 140 lb. Doe last season with a 22--250AI an a 75 grain Berger VLD with a muzzle velocity of 3643 fps. Deer was at 251 yards. Even though there labeled not for hunting. They work perfectly every time. At least in my experience. Picture is off side rib cage
My 22-250 AI hammers deer with a 75g VLD moving 3643 fps. But my all time favorite is a 7mm mag. Having a 28 Nosler built now. Have a feeling it will take over as my new favorite.