I had the elevation turret set screws vibrate loose several times on an EPL4 on my 7 STW. After the 2nd time, I applied medium thread locker and it has not happened since.
Actually, both were shot in the same barrel. It was initially a 7RM that I later rechambered. With a 140 grain bullet and RL22 I run 67-68 grains in 7RM versus 80-81 grains in the STW.
I was watching an episode of Barnwood Builders yesterday where they were rummaging around a home foundation for lost trinkets. Someone asked Johnny Jett what was the best thing he ever found. His answer was Jesus Christ. Me too. Happy Easter all.
I use 19.0 grains of Green Dot for COW fire forming 280AI brass from 280 Rem.
General rule of thumb is to use a charge equal to 1/3 of a normal rifle powder load. Unique should be just fine if you keep the charge low.