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AJ Peacock,
TO some degree it is true that it would be more sensitive to temp changes then H-50BMG.
In your case, with the rifle you will be getting in 338 AM, all powders are somewhat sensitive to temp changes. You put 145 to 150 grains of powder under a 300 gr bullet in a .338 caliber bore you will see some difference when the temp changes no matter what powder you use so I would not be overly worried about this.
Kirby Allen(50)
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Kirby, no worries. Once I run through the H50BMG I have on hand, you'll be putting a new barrel on it for me.
Don