Picked up a couple of pounds of Retumbo to try in my 300 Weatherby, but as of yet haven't tried it yet. I have used Reloader 25 a few times, with some good results, some not so great as of yet.
My Weatherby has a 1 in 9 1/2 twist, and I would realy like to try some Sierra 240's, just to see if they stabilize.
I've gotten 3150 fps using R25 to push a 200 grn SMK, but that got me some pressure signs, so I backed off. Groups just wern't what I wanted either.
I need to decide if I want to stick with the 200 or try the 240 SMK. I like the heavies better at longer ranges....