The Syndicate,
4350 is my favorite powder also. Have used it for years in 22-250, 243, 25-06, 30-06, 7mm and 300WM. Between the three of us (father, brother, myself) we burned up almost 24 pounds of it this summer. My opinion is your powder choice is fine. For an accuracy baseline you may want to try some SMK's.
Also, you may want to repost (start another thread with) this question so the title reflects the subject.
Jim