I have a lot of coyotes running through my cattle. I can easily shoot to 750yds from my front porch. Hit one this morning at 175yd. The furthest I have shot one is 290yd holding over on a standard duplex reticle with a 270. Haven't attempted anything further since I have to hold over. Would like to be able to confidently get out a lot further. So I currently have a new sav 11 22-250 (accu trig/stock) that I would like to be able to shoot to 400 or 500 accurately with. I shoot factory hornady 50 gr SF. What should I sight this gun in at? And is it reasonable to shoot predators out to 500 with this gun and cartridge? Scope is 4-16 standard mildot. (Do I need a different scope). I also have a 15 yr old but never shot Sav 110 270 win (I won it at a ducks unlimited function, it's one of those camo/engraved custom editions). I've bought a Vortex HS LR 4-16x50 off the Optics forum to go on this gun. This scope has the 1/2 moa elevation turret. Proabably shoot 130 or 140gr hornadys. Same questions as above but to 750yds. I understand mil dot and MOA. I just don't want to start shooting at live animals that far out without seeking advice. I will practice on targets first at those ranges. I would rather just scare them than leave them wounded. Basically why I'm asking. Never shot at these distances. Thanks for any knowledge and help with the learning curve.