How much consideration do you experience shooters put into barrel life when choosing a caliber. I don't do any competitive shooting, only hunting. I have a Sendero 7mm Rem Mag that I am finally have all the stuff I need for, just working on a load right now. I am looking for a gun that I can shoot that I can put some rounds through for good ole fashioned practice, but that I can also use for some coyotes. My first choice would be a 22-250. I love everything about it except I have heard that barrel life could be a problem if I am going to want to use this gun as a "practicing" gun also, as I would be putting a descent amount of rounds through it, at least a descent amount of rounds for me anyways. I am thinking about a 52-55gr bullet for this Second choice, 243. I am wondering if the barrel life for these calibers are similar or if one of them outlasts the other easily. I would probably shoot something like the 87gr Berger hunting bullet to take advantage of the little bit bigger caliber and not have any problems extending my range a little. The third choice is a 223 rem. Seems like the barrel life would be great and it would be a good gun for "practicing" but I just don't know if it is quite quick enough to be using on a lot of coyotes. I don't really want to limit my coyote range to 250yds if I don't have to. I am thinking something like a 52-55gr bullet for this caliber. So if anybody can give me any comparisons to barrel life in these calibers as far as a slight guesstimate of number of rounds that would be great. Also, is the 223 a good coyote gun or not? I know they have a lot of popularity for varmints, but I just don't know if it would be enough I guess. Thanks for any input anybody can give me.