I consider the 378 Weatherby an outstanding long range round, particularly when shooting 270 grain projectiles. In fact, it is my favorite LR caliber. I own a 378 WBY short throat with Kreiger barrel, JP recoil eliminator (though if I had to do it over I would go with a Holland QD brake - a bit quieter than the JP, which will disable anyone, including the shooter, standing nearby without ear protection). Shoots half inch at 100, 3200+ fps. Like TSX the best. Has a 5x15 x56 Nightforce scope. Anybody else shoot 378 WBYs at long range? I also own: 338-378 with Pac Nor barrel in MacMillan sniper stock, HOlland Brake, 4x24x50 IOR scope (35 mm body). NIce scope, took a Rusa in New Caledonia half hour after sunset at 4 power. 458 Lott, in Brockman stock, no brake (kicks like a mule, but will shoot 3/4" groups with Swift A frames, 500 grain TSX, and 500 grain Barnes solids). I'm on my third scope, a Burris 1x4x24 now. Blew up two IOR 1.1x4 x24scopes on it. A Browning lever rifle re-chambered in 416 Taylor with Holland Brake, 1.75x 6 Burris scope. 300 Weatherby Accumark, 4x14x50 Nikon sniper scope (sweet scope for the money) AR 10 chambered in 300 WSM with ABS carbon Barrel (not received it yet, but have a 3x15x40 Sightron or 3x18x40 (35 mm body) IOR ready to put on it. 308 Win BAR, 20 inch barel, Browning brake 3x9 Weaver Grand Slam (another nice scope for the money). Kids gun, great set up for young recoil shy kids. 280 AI on Weatherby short action, with Christensen Arms carbon barrel, Bell and Carlsen medalist stock, and titanium brake (another kid gun, specifically for a 100lb. boy who can shoot lights out at over 300 yds., nicknamed Dr. Death by an Australian guide I hunt with).gun) Currently living in West Australia, all guns still in Texas. Lots of brakes on my rifles, but I shoot at ranges hours at a time. Couldn't do that with these calibers without the brakes. Setting up the 458 Lott (round development, scope sight-in, etc.) got me flinching so bad I had to stop shooting for a month.