338 lapua load?

N560 is bad for the throat area in the Lapua

N165 excellent with 250gr
N170 excellent with 300gr

H1000, RL 25 and Retumbo excellent in 338 Lapua

RL 33 is made just for the 338 Lapua
Not on my shelf yet.
 
have you used 250 gr SMK on big game ?

No I haven't. The 300 gr. SMKs performed better accuracy wise and ballisticaly so I use them. I had 3 kills on deer last year at over 500 yards. All three took out the top of the heart and spine. Two droped in their tracks and one cartwheeled down the side of a steep hill.

But I'm sure the 250 would probably work for you also.
 
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