Last spring I was fortunate enough to get a shot at a big black bear. I had my 35 Whelen with 225gr. TSX. The shot was 25yds.
I shot as he was facing towards me, head down. He was in the same position as he is in the pic beside the barrel. At the shot he went straight down and never twitched, except three death rattles.
I aimed between his shoulders, at the base of the neck. The bullet went through the spine and neck, all the vitals, and I found it against the hide where his offside back leg started. I did a quick measure and the bullet travelled 34", or close to it.
Even though the bullet sheared 3 petals off, I am still really happy with it's performance. It went through alot of meat and bone, and penetrated a long ways.
My muzzle velocity is 2660fps, and at 25 yds it wouldn't have been much slower than that.