I took a cow last year with my 7mm Rem mag and 160 gr. AccuBonds. I intentionally wanted a cow for the excellant low- cholesterol meat. They normally eat much better than an old bull.
We were hunting in high winds and my shot came at 317 yards in the trees (lasered later). I hit her too far back on the first shot and she moved about 10 yards and stopped, too sick to continue as the herd moved off. The second shot was a bang flop, close behind the front shoulder.
Both bullets were recovered under the hide on the far side and weighed 105 and 110 grs. nicely mushroomed. The first shot had hit her through the liver making her sick. There was very little blood-shot meat.
The load was 65.5 grs. of RL-22 ahead of a F-215 primer in WW cases. loaded .030 off the lands. velocity was just slightly under 3,000 fps, 2975 or so. This load shoots sub-moa in my rifle out to the limits of our 300 yard range. It is also very flat shooting. +2" @ 100, +2"" @ 200 and -2" @ 300. Pressures appeared very mild, I also tried 66 grs. pressures which also appeared mild enough and velocity was over 3,000 fps. but there was no noticeable difference on the targets except for about 40 fps so I stayed with the milder load in order to avoid any problems on the hunt. I'm going to shoot the same load next year. It's a winner.