I guess I'm "Old School", so i only use bolt action rifles. I use a .243 with 87 vmaxes, a .223 AI with a 55 vmax and a 6AI with a 87 vmax. I got 2 .308's this year and am shooting a 110 vmax just for fun. They really blow up 2 liter plastic bottles at 200 yards!
If i want to save a pelt I like the .223 AI. If you dont hit bone, little bitty hole in, no hole out!
My best ever day on 'yotes was back in early 90's in NCentral SD while scouting for deer season. Saw 11 shot at 9 and killed 8. The back of my CJ-7 was a little ripe on that ride home. Remington 700 rechambered to 257 Wby