As Bounty Hunter stated, as shelf full of different bullets and powders to provide you with about 100+ combination should get you there along with 3 days a week for maybe 2 months to REALLY get you satisfied for your rifle as every rifle shoots a little different.
I have 2 of those CVA's. One of the older (safe) ones (as some were not) with a 21" barrel. 2 pellets and a 250 Barnes <1"at 100 all day long at 1700fps. The other load is 100 grains of real black powder and a 260 .45 cal Speer hot-core w/Harvester sabot 1560fps and under 1" at a 100 yards too.
My other CVA a newer Kodiak-Pro 28" barrel really likes the 250 grain PTX with 2 pellets for 2000fps and under 1" at a 100yrds.
Probably the most important piece of info I can give you is to seat the bullet to the powder CONSTANTLY with the same pressure as I've found this to be a very important factor.
Also I use the Clean Shot round pellets that are no longer made due to Hodgon suing Clean-Shot hence American Pioneer Powder now, for patent infringement on the round design. That's why the tapered stick design (shhessh).Must have had a really lousy lawyer. I bought up all the guy had a gun show, 6#'s for $10 a pound.
The Triple Seven always gave me a powder ring after 2 firings that was a bitch to push thru and that is why they developed the muzzleloading primers. I didn't get the consistency needed either for good groups.
The primer I use are the new Winchester Muzzleloader 209's.
By the way the Burris 4.5x14 I bought for my sons 25-06 found it way on my muzzleloader (Kodiak) and the Ballistic Plex marks work out to within 2" of aim/impact out to 225 yards.
You'll probably find that the Barnes MZ bullets will shoot very well to eliminate a lot of bullet searching, I don't like 300's unless I'm going for elk, but they do shoot. They are a buck apiece.
Good luck and enjoy a load work up. Remember CONSISTENT seating pressure.
Here is why the $159 CVA's shoot. They hired Ed Shilen from the USA