While most guns are now rated for 150gr powder, few of them actually shoot anything accurately with that charge. If you want to shoot long range, accuracy is more important than maxing out your velocity.
When I got my Omega, I accurized it (bedded/pillars) and ran every high BC offered in 2004 through it (ie everything out there now but the TMZ). The flattest-shooting accurate load I found was the 200gr Shockwave over 110gr FFg 777 at 2100fps. I took a doe with a pass-thru at 338 yds last fall using this load -- 2 more at 180 and 209 just minutes before that. You're not going to reach much further than that with any load, 150gr or not.