Re: Rem 700 VLS
You should be in the ball park with the set up you have. I'd glass bed the action, but depending on the gun itself and the reticle on your scope, you should be able to ventilate a varmint at 500. Some remmys are great right out of the box (if it's had the trigger tuned and barrel floated, I'd bet that it's a good one, unless someone already shot out the barrel), others need to be rebarreled, trued etc. If you've got a good one, all you should need is to work up a good load/find the ammo it likes. The 22-250 has a big selection of bullets to chose from, so it may take a bunch of shooting to figure out what it likes to eat. Once you do, it should shoot like a champ.
I like things that go "bang"... I love things that go "BOOM!"