my first rifle was a 243, so shot alot with that. I shot a 34 lbs. a couple of days ago w/223 62 gr. tsx, point of shoulder, DRT.broke opposite leg on way out,like my 257wm w/85 bt.340 wm does a good job on them to, shot one last year w/325 head shot, blew his eye out, you get the idea, I shot em with what is handy
I've got a 6mm-250 that does very nicely w/ Hornady 75 gr HPs and a 257 AI that shoots 75 gr VMaxes as well as 100 gr Speer HPs for heavier varmints.
I use either a .223 or a 6/250AI. Used to use a 6mm Remington, but have now gone with the 6/250AI. The round fits shorter actions a little better, and cases are easy to find. My next barrel will be for a 1.49 (about that) shoulder deminsion with a 2.00 overall length. But I might do it with a 6mmAI reamer ran into the barrel a little short (actually way short), and then form case out of generic .243 brass.
7mm stw and a 300rum. I finally had them quite running with them. tried 204, 223, 22-250, 243, 6.5x284 and kept gettting runners???? they finally quite after jumping to a 162gr. amax @3100
I've never had a single dog get up and run after hitting it with the 6mm Remington. With 80 grain Sierras the dog was often cut in half. I have had them get up and run with a 22-250, but I've got a new bullet combo that may relieve that situation. The results with a .223 were actually better than the 22-250 under 300 yards (most all my shots are under 350 yards). We see a lot of coyotes in the 30 to 35lb. range around here, and every once in awhile a 40lb. dog. I just can't imagine ever needing anything bigger than the 80 grain Seirra as the distruction is horrible