"Thread Drift" is OK as long as it doesn't drift into politics.
I am farily sure I'll go with .22-250 for coyotes in a new Ruger American. So far it is, on average of all tests I've seen, one of the most accurate "inexpensive" rifles out there. I wish they made it with a stainless steel barrel so I could get several hundred more rounds from it.
I have some heavier .22 cal bullets I'll load up and see how they like the factory twist.
For sure I'll Fire Lap the barrel as soon as I get it. A smoothly lapped bore just seems to shoot more consistently, plus it fouls up more slowly.