Re: 22/250 or 223
the only reason I would go with a 223 is if i wanted an AR sure is nice to have that semi-auto when you miss or have 2 dogs. i have both an AR and savage 22-250 if you decide 223 then definitely make it an AR, if AR's aren't your thing then id say 22-250, if your reloading cost difference is so small you might as well go 250 for the extra punch.
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