As a point of refence, a friend of mine who hunts alot tried to use a 17HMR on racoons. He was shining them up in the trees and shooting them. After 3 out of the first 4 coons hit the ground still alive and escaped, he went back to his old reliable 22LR and killed 6 straight with no issues.
I have never owned or shot one but based on what my buddy saw, it may be a bit marginal. However, like the previous post said, shot placement is critical. Shooting a coyote in broad daylight versus a coon in the dark may not be the best comparison.
Not sure this answers anything

....just informational.