In 2009 I with a group of friends all experienced hunters. One of them with the 375 jdj has a phd and retired out of the Idaho Fish and Game. Needless to say he understands shot placement and hunting. He tried to hunt expressly with the 375. To make a long story short it sure was the best on the paper, it was the best on the flight over and it was going to be the best gun out of all. We all took only handguns. Well that best gun ended up being disposed of and he borrowed my 500 s&w. In Africa if you wound a animal you pay for it just like you killed it. I guess 2 wounded Cape Buffalo's at 12 grand a piece is enough to piss a person off. All I can say is the 500 S&W loaded with a 375gr Barnes bullet dropped all of the Buffalo in one shot. Including The owner of the 375 jdj 3rd buff. The 375jdj never came back to the USA. It was left to the PH as a tip.