I have loaded a number of calibers with N550. I have used it in a couple of 30-06's with very good results shooting 150 Nosler Partitions and 168 TSX's.
At one time N550 was the powder that I used most in my 300 WSM
's. It worked well behind the 168 TSX's.
I have also used it in my 308 behind 168 Sierra Match bullets. I was able to get good accuracy and speed.