Originally Posted by jfseaman
And it's more complicated.
it can be done but it's not advisable to do it off hand, I have one load that I interchange bullets of the same weight, which bullet depends on what I'm shooting at. BUT each and every load was was worked up individually and just happened to give the best accuracy at the same charge weight, same powder same primer. I should also point out that, that particular rifle has throat erosion bad enough that not one of the bullets used in it can touch the rifling and still be touching the case neck.
Keep in mind the animals we shoot for food and display are not bullet proof. Contrary to popular belief, they bleed and die just like they did a hundred years ago. Being competent with a given rifle is far more important than impressive ballistics and poor shootability. High velocity misses never put a steak in the freezer.