The best powder I have tried is RE25, it proved very consistent in both pressure and top velocity in my custom Model 70 with 26" barrel.
All bullet weights from 200gr - 250gr have grouped very well, averaging .25-.5 MoA over a 10 shot group. I don't see the point of a 180gr bullet in this calibre.
I will not post the actual loads on here, some would say they are hot, but my pressure trace II would disagree!
The biggest aspect of getting this powder to work consistently is packing scheme, all cases need to be loaded to the same height in the case. I use the 'swirl charge' method to expedite this. I dump into the pan and then swirl pour into case using a funnel. 'As dumped' charges will not do this with this powder!