I was in the same boat as you a few months ago and couldnt find too much load info. for this cartridge/bullet combo.
The rifle im shooting is a Tikka
The best load I was able to find was 35gr of Varget. It shoots a bit under 1/2" @ 100 yds I havent had the chance to really play with seating depth etc. so hopefully I can get some time to wring out this load a little more and see what happens. I want to shoot hogs with it as well. Hopefully it'll happen in the very near future
The specifics are as follows:
Cal: 22-250 Rem.
Bullet: 53 gr. TSX
Powder: 35 gr. Varget
Brass: PMC-Once Fired ***Note..Only Brass I had access too but have since picked up
some winchester brass to try.
Primer: Rem. 9 1/2
I did find something unexpected though, when I used my stoney point gage to get a rough est. on OAL with the bullet touching the lands so I could set my seater. The bullet was literally all the way out of the case neck before touching the lands so my loads are way off the recommended .050" but theyre doing good enough for what I intend to use them for.
Hope this helped a little.
***This load shown here is safe only in the gun for which it was developed. I do not assume any liability for accidents or injury resulting from the use or misuse of this data.***