I've been toying with Re 17 and the 162 gr Amax recently. I got up to 45.5 grs and groups were starting to tighten up nicely. Not a hint of any pressure signs and velocity was in the 2680 range out of a 23" barrel.
Have a test loaded up from 46 to 48 grs in .3 gr increments, but it just to sloppy out to get to where I shoot. As a foot note, 48 grs is a pretty compressed load of Re 17, crunches pretty good when you seat the bullet but doesn't push the bullet back out even after sitting around for a few weeks.
Ignorance can be treated with education, sadly there is no cure for stupidity.