I've been using about 10.7 gr of Trail Boss with a 190 SMK and have had good luck. No need to drill out the flash holes IMHO. I am actually thinking of going to a heavier bullet like around 200-205 to see how they do. I tried some 220 SMKs but I thought I saw a little keyholing with my Rem 700 AAC 1:10 so I gave up on them. Didn't really cherish the idea of sending an expensive suppressor downrange.
I don't see a need for magnum primers. I've been using WLRs and they work just fine. I think that you'll probably want to go to a heavy bullet. At least you'll be carrying a little more energy down range.
I haven't tried these on deer or hogs yet. Seems like there's two schools of thought as to whether these are adequate for medium size game.
Awesome results with 10.8, going to work up and see where the breaking point is, I don't have chrono, was using 180 gr, only shot 50m, will push it out this weekend. Know what you meet about trashing a suppresor!