Not the same cartridge/caliber, but I shoot a lot of RL-22 for my 7mm Rem. I my 257 WSM I have shot a lot H414, but that is more because I have a lot of it in my arsenal. It shoots good enough and I didn't notice much variance with other more "case filling" powders. I do really like the H414 because it measures SOOOOOO easy compared to chopping the RL-22 in the powder measure.
I HAVE NOT VERIFIED THIS, but this guy says it is his favorite load for his 300 WSM
67.0 grReloder 22 3,000 fps2.84" Fed LR guestThis is the most accurate powder bullet combination load I have been able to get for my Savage 12BVSS 300 WSM. I get 1/4 inch groups @ 100 yards using Hornady 180 gr. SST with 67.0 grs. of RL-22 using Winchester brass, Federal Large Rifle Match primers.
Be aware too, (and I have not personally had this problem), they claim that RL-22 is both temperature sensitive and can vary quite a bit from lot to lot. I have shot probably 20-25 lbs of this over they year and no problem, but just search for RL-22 and varying and you will find quite a bit of posts.
RL-22 is a favorite of mine though...