Two red flags
I've loaded for 300 RUM . Shot a Bear with that bad boy MAGNUM PRIMERS ONLY
Those heavy bullets don't go near any 4350. Reloader22 would be the fastest powder I'd use. Retumbo was the powder that worked the best for my self. 95grs of Retumbo with Rem Magnum 9 1/2 primer 200 gr Accubond produced 3,200 FPS and a dead Bear. So H1000, Re 25, Retumbo, Hodgen 869.
How does it profit a man if he gains the whole world but loses his soul?