While I can't comment on the Weatherby, I changed the load after many years of shooting the 115gr PT over to the 110 AB when I passed my 25-06 over to my daughter two years ago. The load is running just under 3200fps and easily groups around 1/2" at 200yds. I could run the velocity up a little more but with that accuracy there is no need.
She has since taken several feral hogs a couple of yotes and a nice 10 point nice buck this past season using the AB all with DRT results at various ranges.
These were almost in her lap when they jumped them from some thick brush. First shot was around 5yds and the second might have been out around 50 at most.
This one was over 200yds at night while checking a hog trap with a spotlight. He was hit just above and between the eyes. Trust me this is the pretty side.
She got this decent buck the last day of the season this past year at around 150yds. I was very impressed with the internal damage done with out having to trim away any meat. Entrance was just behind the left shoulder and exit was through the left. the hole was about the size of a quarter.
I just had a 25-06 A.I built and depending on how well they shoot that may also be my choice of bullet. I also have a few of the heavy Wildcats to give a whirl.
Good luck with your rig, I am sure that if you go with the AB you will not be disappointed by the results. If they had been out 20 yrs ago they would have been my mainstay for the other rifle I am sure. A 120gr in this caliber would be awesome.