I have used 48 gr of RL 22 in my 243 ack with decent groups but to be honest I was only getting like 3200fps out of that load and it just didn't make sense to shoot them when I could get 3300 fps from the 105 gr AMAX. I'm sure its from the slow powder but why waste the time. I'm now strongly considering the nosler 70 ballistic tip with maybe varget?. I haven't run the numbers yet but 3200 fps with the 87 vmax vs. 3600+ with the 70 gr ballistic tips would be pretty interesting to see who's the winner. Now I think I know why so many varmint hunters use the 70 gr BT.