I haven't tried the 75 & 80 grain Berger VLD's in my 22/250AI, but have tried the 75 grain Amax and 80 grain MK.
Reloader 22, Vihtavouri N165, and H4831sc are good powders with the 75 grain bullet weight, and I suggest starting at about 39.0 grains and work up to max. These powders could also be used with the 80 grain bullet.
Reloader 25, and H1000 worked well with the 80 grain MK in my 22/250AI, as the case had just enough capacity to allow both powders to reach near maximum pressure. I suggest working up from about 41.0 grains with either powder. Hope that the above helps. Brian.