I shoot a 22-6mm (aka 224 TTH) with an 8-twist tube - similar case capacity to your round. My best luck has been with 75 Amax and 77 Sierras. I haven't tried anything lighter than 60 grains yet - I have a 22-250 that shoots the lighter stuff lights out, and this round has enough horsepower to handle much heavier.
Based on my experience, you'll want to forego medium burn rate powders and concentrate on the slow numbers. My best loads were with RL22 and H4831SC with the 77 gr Sierra.
The hot 22s will typically tear apart lightly constructed bullets, especially with fast twist barrels, so you'll need to stick with stouter bullets if you're going to use the light weights. It's pretty funny when you realize that you missed the target because the little puff out there part way to the target board is your bullet disintegrating