In my opinion more than one should be tried. I did have issues with a brick of purple gob GM215s I got about 5 years ago, but have been happy with them since.
I haven't found theory to be all that useful for minimal vertical at long range.
I use FedGM215's with H4831sc in a 25-06. I only put it on paper once at 1K, 6 shots printed under 4 inches of vertical, I figured I didn't need to do anymore.
But I use CCI-BR2's with H4831sc in 6.5x284.
And FedGM215's with H4350 in 300 WSM
That said, when I load the next one, I may not end up with the same result.
I run them across a chrono, cuz it's cool. But I really don't trust a thing about it. Some days the numbers look good, some days they don't. However, paper is pretty consistant.
Having found the charge I want with primer A, I do load development again with primer B,
I agg. five or six three shot groups of each comparison load at 500yds. The smallest vertical average group size gets shot.