You say you want to try something different? You might consider the 230 gr Berger target hybrid. This bullet is the highest BC of the production 30 cals. It would be great for LR targets or hunting. (read Broz' experience with it last year Berger 230 and 300 OTM Hybrid terminal results
Try the BC in your ballistics program and compare to 208 or 210 VLD to this:
230 berger target hybrid .743 (G1) .380 (G7)
While many are running H-1000 or Retumbo with their 30-378s you might want to give the new RL-33 a try. RL-33 has a long burning curve similar to RL-17's and is slower than Retumbo. I didn't have load data for my rifles but once I realized the approx burn rate I used Retumbo's higher charge weights as a starting point in several rifles. (6mm-284, 7 rem mag, 257 weatherby and 300 RUM)
The 300 RUM and got amazing velocity with a 24" barrel (long story on why this short barrel) and the 230s. 100 gr of RL-33 2975 fps. Imagine what your rifle could do! You will definately get over 3000 fps.