R. Dean, I would go with a Remington. If you ever decide to build a custom rifle
, Remington actions can be worked on and turned into an action almost as good as custom ones. Both rifles have big barrels, however, I do think the muzzle dia. on the Savage is a bit larger. I believe the Remington muzzle dia. is .830 and the Savage is .925 at the muzzle. As far as price, I think the Remington VSSF runs around $950.00 and the Savage is around $550.00.
Regarding ammunition, with a 1-12 twist barrel, I would go with something offering a 50grn pill. My friend has a 22-250 in the new Remington VSSF and he shoots factory loads with the 50grn V-MAX. His gun is wicked accurate with that bullet, he also shoots the 50grn ballistic Silver tip and it's accurate too. I don't now what brand the 50grn V-MAX load is, but I belive the 50grn Ballistic Silver tip is Winchester. If I were you, I would buy the Remington over the Savage anyday, but if it comes down to money the Savage is hard to beat.
Regarding bi-pods-I own four Harris bi-pods and I love this product. They are expensive, but worth it.
Regarding optics-Get the best that you can afford, hence, if you go with a Savage Rifle you could spend more money on optics. However, if money is not an object on this project go with Nightforce or Leupold.
Good luck with your choices and let us know what you decide on.