7-08 is a proven caliber. I know a few Canadians that use it on moose. I met a native in BC who had a 7-08 he used with Barnes 120s to kill moose. Point being, if it will kill a moose, it will also serve you well for deer.
I know a few hunters who load 150 btips in theirs and have plenty of pics and meat in the freezer.
I don't own one and if I did, I'd try the 150 btip, 140 btip, and 150 scirocco. Also on the menu would be a 168 VLD and 140 TTSX.
Varget, 4064, 414, and 4350 would be my first powder choices. Maybe Reloder 19 as well.