Some people will say different shooting positions while using a bipod will change the POI...
So it stands to reason that they would think a totally different set-up would change the POI.
I don't use a bipod, but I do shoot in every shooting position I can fathom; I don't see a POI change from one shot to another.
I simply make sure the fore-end is rested on something, (hand, log, fence,) foward of the trigger guard. If shooting prone, the rear will either be rested on a beanbag or hand, at or near the strap swivel.
I think you'll find that most people will not report a change in POI.