Yup, I'd have no qualms shooting it without a break. Afterall, I shoot my .416 Rigby CZ550 PRONE off of a Harris Bi-Pod with no brake......the load is a 350gr. Barnes TSX at 2750 fps. I had to go to a McMillian stock since the wood one started splitting.
As you can see, I removed the factory sights and re-contoured the rear sight "block", then sand-blasted the barrel and re-blued it. It wears a 4.5-14x50mm Vari-X III.