It is always nice to be able to check/rezero in the conditions you'll be hunting. The big issue is of course drop figures. If your lucky you can take a couple of shots in the field at distance to confirm your new conditions dope.
Confirm when you get there, if possible. I just did the same thing going from 1000' to 8000' I used an online ballistic table to create a drop table for the higher altitude (thinner air) but had to guess at a reduced velocity due to lower temperature. I took my chronograph with me and found velocities higher than I had guessed. Net effect was about one inch off at 100 yards. Check it when you get there.