I have toyed with the idea from time to time. They reduce recoil almost as well as a good muzzle brake
, and (obviously) are much quieter. Just yesterday I was shooting a friends SR-25 MK11 Mod 0 with supressor in place. Shooting 175gr Federal Gold medal ammo was almost as quiet as stardard velocity 22lr ammo. I was supprised to see a 60fps improvement with the supressor on. Precision was about the same, 1/2-3/4moa or so out to 300... the furthest we shot it with the can.
The big downer is that most, if not all states have laws restricting the use of supressors for hunting. Not exactly logical... but then again, not a lot of laws are.