With the availability of some of the newer bullet designs and some of the newer powders, I think the 30-06 deserves a second look. Of course, the same components can be applied to the various .300 Magnums to provide a similar boost.
Still, using the latest reloading components, the good ole' 30-06 deserves more respect than it gets, IMO.
Though his writing is mostly geared to long range target shooting, I highly recommend Mr. German Salazar's writings on the subject. You may find what he has to say to be eye-opening. He has posted a lot of information regarding the 30-06 on his blog: The Rifleman's Journal