Re: What's do you think the best all-around cartridge...
7mm Remington Magnum!
Perfect ballance of efficiency and horsepower. Not oversized for deer or antelope yet it can easily handle the largest game in the US. Fantastic selection of high BC bullets and an extremely broad and useable range of bullet weights. The .300 Win Mag would have to be right there with it but I think the BC and velocity of a 7mm 168-180 gr. beats out the .300 trying to throw the larger pills with comparable BC.
Now it's time fore me to go. The Autumn moon lights my way.