Re: Taking animals with long range target bullets
If you use the 105gr Bergers in the 243 and find the highest velocity node your gun will allow, they will offer plenty of downrange energy. I have been surprised that the 105 and even 95gr VLD's penetrate half way through a 1/2" piece of 410 stainless steel plate at 300 yards. They make a much deeper impression than a 175gr SMK at the same range from my 308.
As others have said, shot placement is key. I don't believe there is a bullet out there that can compensate for a bad hit. Once you have a good hit, I personally doubt that 1 bullet vs another is really going to have a substantial effect on the outcome. Now if you are facing down an elephant/Cape buffalo at 30 ft, I might want to have the best bullets money can buy but most of us will never be in that situation.