My response to this would be that I took a Rem 700 LH in 338 Win Mag stuck a brake on it, redid the outside of the stock plus pillar bedded. Shot exceptionally well with 225s and 250s.
However, Win Mag just wasn't 'nifty' enough so I had a local smith fit a 26" Rem 338 RUM new take off barrel that I got from Kirby Allen for next to about nuthin'. Had the brake moved to it also.
Doesn't shoot 225s or 250s very well but does wonders with 300 SMKs.
It's my carry gun but is tuned to go 875 yds.
The only reason for not going farther is limitations of the Mil Dot reticle and 1/8th minute clicks that I don't trust and certainly can't count.
Your largest consideration is weight. Heavier just seems better the farther ya shoot. But that isn't always the case.
Give it a go.....and see what happens.