I shot 3 deer this year with the 180 gr SMKs out of a 300 WSM
The first 2 were mule deer (200 lbs) taken at 324 lasered yards, both hit high ribcage both striking a rib on the way in. Neither bullet penetrated the skin on the opposite side but caused mass destruction of the internals.
The 3rd was a white tail (175 lbs) shot at 150 yards in the high ribcage. Bullet didn't strike any bones and exited the opposite side with a tennis ball side hole.
All 3 bucks (8, 9 and 10 pointers) dropped right in their tracks!