IMO, I would not use the Dead Center.
If you are planning on high velocity for long range then a close impact will be like a varmint bullet!
Smokeless is NOT like BP to ignite.
Anything too loose and all you will get is poof :( ( this only happens on big bucks
I have used the Dead Center bullets and found them deadly accurate at the range, but did encounter a misfire while hunting. I attribute this to the soft lead conforming to the bore over time and in effect making a loose load.
I admit that the powder I was using may not have been optimum for ignition, but yours may not be either.
I hit a small deer at around 200 yards with a MV around 2500+
The results were not pretty and penetration was minimal....but it was a dead deer.
If you like to tinker then the Savage will give you a lot to tinker with.
As a side note, the Vent liner wears fairly quickly and the ID should be checked about every 25 shots. It starts at around 0.031 and once it passes about 0.037 accuracy will normally start to go south.
In that same vein, you either need to keep the breechplug free of carbon by drilling it out every 30 - 100 shots OR you never clean it until you can't load a primer without crushing it. Then you only clean out the nipple area.
Clean can be accurate and dirty can be accurate, but in-between while it cruds up you will tear your hair out